MyBioSource.com's PACSIN1 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
PACSINs are members of a family of cytoplasmic adapter proteins, which share a conserved C-terminal protein binding SH3 domain and a CDC15-NT domain. PACSIN 1-related proteins include syndapin 1 (the rat homolog of PACSIN 1), FAP52, EM13, and PSTPIP, all of which seem to be involved in signaling pathways associated with cytoskeletal organization. PACSIN 1 expression is restricted to terminally differentiated neural tissue, whereas PACSIN 2 is widely expressed. PACSIN 2 shows vesicle-like distribution and may be involved in regulating endocytotic processes